He then heads to Asia where he will briefly join US President Barack Obama in Vietnam, the Associated Press reported on Saturday.
Just a day after he returned from Paris and London, the State Department said Kerry departed on Friday for Jeddah, Saudi Arabia.
From there, he travels to Vienna for meetings on Syria, Libya and tensions between Armenia and Azerbaijan over the disputed enclave of Nagorno-Karabakh. He will then visit Brussels for a meeting of NATO foreign ministers and then fly to Asia.
Before meeting Obama in Vietnam, Kerry will make a short stop in Myanmar.