This is the fifth time Iran has qualified for a World Cup, but has never advanced to next stage.
Iran was the first Asian team to secure its place at the FIFA World Cup 2018.
Currently the best-ranked Asian team, Team Melli will be aiming to advance past the group stage in Russia next year - having seen its interest ends in the preliminary round in its previous appearances.
A famous 2-1 defeat of USA at France 1998 marks Iran's only win in its four previous FIFA World Cup appearances.