Boko Haram has attacked Niger, Chad and Cameroon from its base in northeast Nigeria.
Niger's defense ministry said in a statement on Wednesday that the army mounted a sweep operation against the group last Friday along the southeastern Komadugu River, which separates Niger from Nigeria, Reuters reported.
More than 200 militants were "neutralized" by air strikes and 87 were killed by Nigerien troops on the ground, it said.
In June 2016, more than 30 Nigerien soldiers were killed during a Boko Haram attack on the town of Bosso, prompting Chad to send 2,000 troops to help its West African neighbor counter the militants.
Those troops were withdrawn in October 2017, raising concern about security in the Diffa region.