The National Demonstration for Palestine followed a week-long exchange of air raids and rockets that killed at least 25 Palestinians and four Israelis.
Protesters gathered at Portland Place and marched to Whitehall, where several speakers delivered speeches to the crowd.
Palestinian ambassador to the UK Dr Husam Zomlot stood on the stage next to Ahed Tamimi, the protester who became a globally known after slapping an Israeli soldier in the West Bank last year.
The event was timed to coincide with a day commemorating the Nakba or “catastrophe” which led to the exodus of several hundred thousand Palestinians following declaration of the State of Israel on 15 May 1948.
Demonstrators said they believed Benjamin Netanyahu’s election promise to annex the West Bank and Mr Trump’s plans for peace in the region – which he has dubbed the “deal of the century” – were key obstacles to the realization of Palestinian rights.
