The 24-year-old forward currently plays for Goiás on loan from Bulgarian club Ludogorets.
The Iranian club has confirmed that it has reached an agreement with Brandao, futebolinterior.com.br reported.
Persepolis is going to find a replacement for its Croatian forward Mario Budimir.
Brandão started his playing career at Brazilian club Atletico Juventus in 2015 and has also played for Brazilian clubs Ferroviaria, Novo Hamburgo and Primavera.
Persepolis will start the new season of the Iran Professional League with a match against Pars Jonoubi on August 22.