Ehsan Haji Safi scored the solitary goal of the match in the first half stoppage time.
Elsewhere, Saipa was held to a 0-0 draw against Gol Gohar and Pars Jonoubi and Zob Ahan played out a goalless draw.
In Ghaemshahr, Nassaji defeated Paykan 4-3.
Sepahan sits top of the table at the end of week two with six points on goal difference.
Padideh and Nassaji are second and third.