Ghazal Soltani lost to Moroccan practitioner Oumaima El Bouchti in the -53kg final match and seized a silver medal.
Nahid Kiani and Melika Mirhosseini also claimed two bronze medals in -57 and -67kg weight categories.
On Day 1 of the competition, Zahra Pouresmaeil won a gold medal after defeating Spanish Tania Castineira Etcheverria at the +73 kg final.
Yalda Valinejhad and Parisa Jaavdi also claimed two bronze medals at the -62kg category.
Turkish Open Taekwondo Tournament is considered as WTF G1, where the gold winner earns 10 points and finalist and bronze medal winner accumulate 6 and 3.6 points.