Esteghlal will host Tractor in Tehran, while Persepolis play the Iranian first-tier football team Van Pars Isfahan in Tehran.
Hazfi Cup is the Iranian football knockout cup competition, run by the Iranian Football Federation. Esteghal is the most successful club with seven titles.
Nassaji Mazandaran is the titleholder.
Iran’s Hazfi Cup Round of 16 will be held on January 10 and 11.
The draw in full:
*Esteghlal v Tractor
*Persepolis v Van Pars Isfahan
*Havadar v Chadormalu
*Foolad v Khoosheh Talaei
*Arman Gohar Sirjan v Esteghlal Mollasani
*Gol Gohar Sirjan v Mes Shahr Babak
*Malavan Bandar Anzali v Naft Masjed Soleyman
* Be'sat Kermanshah v Navad Oroumiyeh
*Pars Jonoubi Jam v Iman Sabz Shiraz
*Mes Rafsanjan v Zob Ahan Isfahan
*Paykan v Esteghlal Khuzestan
*Mes Kerman v Sanat Naft Abadan
*Nassaji Mazandaran v Fajr Sepasi Shiraz
*Sepahan Isfahan v Saipa
*Shahrdari Hamedan v Darya Caspian Babol
*Ario Eslamshahr v Aluminum Arak