The draw ceremony will be held in Kuala Lumpur, Malaysia.

Inaugural AFC Champions League winner Al Ain of the UAE, Uzbekistan's FC Nasaf, Two-time AFC Champions League winners Al Hilal and Al Ittihad, Al Nassr and debutant Al Fayha of Saudi Arabia, Navbahor of Uzbekistan and Iran’s Sepahan have qualified for Round of 16 from the West Zone.

Iran’s Nassaji and Persepolis failed to book their place in the knock out round.