Iran is runner-up, which could possibly see the team advancing as one of the best five second-placed teams.
With DPR Korea having confirmed itself as the group winner, both Syria and Iran - tied on three points - needed victory in the race to finish as the runners-up and possibly advance to the Finals.
Forward Mahan Alipour struck the only goal of the game in the 20th minute to seal the points and second place for Iran, who meets Jordan in their concluding tie on Sunday.
Syria face Hong Kong with neither in a position to overtake Iran due to their respective head-to-head records against the Central Asian side.