The forward netted nine goals in UAE side Shabab Al Ahli's run to the quarter-finals.
In his first season with Shabab Al Ahli, four of Iran striker's goals came in the Round of 16 win against Jordan's Al Wehdat.
He also scored once in the first leg of the quarter-final against Sharjah FC but it was Shabab Al Ahli's local rival who advanced to the semi-finals after winning the penalty shootout 5-4, with the tie having ended 2-2 on aggregate.
Azmoun finished one goal ahead of Tractor FC's Amirhossein Hosseinzadeh and Shawal Anuar of Lion City Sailors FC.