After three years of negotiations, the legally binding pact was adopted by the World Health Assembly in Geneva. WHO member countries welcomed its passing with applause, Reuters reported.
The pact is widely seen as a victory for members of the global health agency at a time when multilateral organizations like the WHO have been battered by sharp cuts in US foreign funding.
"The agreement is a victory for public health, science and multilateral action. It will ensure we, collectively, can better protect the world from future pandemic threats," said WHO Director General Tedros Adhanom Ghebreyesus.
The treaty faced a late challenge on Monday when Slovakia called for a vote, as its COVID-19 vaccine-sceptic prime minister demanded that his country challenge the adoption of the agreement.
One hundred and twenty-four countries voted in favor, no countries voted against, while 11 countries, including Poland, Italy, Russia, and Slovakia, abstained.