Mohammad Hossein Derakhshani, Hossein Tayebi, Mahdi Karimi and Hossein Sabzi were on target for Iran.
Idris Yorov scored a consolation goal for Tajikistan.
Earlier in day, Morocco defeated Afghanistan 4-0 in Group B and qualified for semifinals as the top team.
The futsal tournament of the 6th Islamic Solidarity Games runs from November 4 to 21, 2025.
Group A includes Saudi Arabia, Uzbekistan, Libya, and Azerbaijan.
The event has brought together more than 3,000 athletes from 57 nations, competing across 25 sports in pursuit of glory at one of the Islamic world’s premier multi-sport events.