Masoud Yousef, Salar Aghapour, Moslem Oladghobad and Ali Khalilvand were on target for Iran and Shakhzodjon Sadiev and Akbar Usmonov scored for Uzbekistan.
Iran will play the winner of Morocco and Saudi Arabia in the final match.
The futsal tournament of the 6th Islamic Solidarity Games runs from November 4 to 21, 2025.
The event has brought together more than 3,000 athletes from 57 nations, competing across 25 sports in pursuit of glory at one of the Islamic world’s premier multi-sport events.