Takaichi sparked a diplomatic row with Beijing with comments in parliament last week that a Chinese attack on Taiwan could amount to a "survival-threatening situation" and trigger a military response from Tokyo.
China's top diplomat in Osaka shared a news article about Takaichi's remarks about Taiwan on X and commented "the dirty neck that sticks itself in must be cut off", prompting a protest from Japan's embassy in Beijing to Chinese Vice Foreign Minister Sun Weidong.
Chinese Defense Ministry spokesperson Jiang Bin said that Takaichi's words were extremely irresponsible and dangerous, Reuters reported.
"Should the Japanese side fail to draw lessons from history and dare to take a risk, or even use force to interfere in the Taiwan question, it will only suffer a crushing defeat against the steel-willed People's Liberation Army and pay a heavy price," Jiang said in a statement.
On Thursday, Sun summoned Japan's Ambassador to China, Kenji Kanasugi, to lodge a "strong protest" over Takaichi's remarks.
It was the first time in more than two years that Beijing has called in a Japanese ambassador. Sun last summoned then-ambassador Hideo Tarumi in August 2023 over Japan's decision to release wastewater from the Fukushima Daiichi nuclear power plant into the sea.
China's Foreign Ministry on Friday also expressed "serious concerns" about Japan's recent military and security moves, including ambiguity over its non-nuclear principles.