Social media footages showed thick black smoke engulfing the warehouse located along Abu Baker Al Siddique Street behind Al Khabayl Discount Centre in Al Khabeisi area.
Dubai Media Office tweeted that the fire broke out in a plastic materials warehouse. " Dubai Civil Defense teams are currently dealing with a fire at a plastic materials warehouse in Port Said area. No injuries reported from the incident," says the Media office tweet.
A Dubai Civil Defence official said the fire started in a printing press warehouse business located behind the mall, NationalNews reported.
He said all occupants escaped the building safely before the fire took hold. The blaze briefly led to traffic congestion, which has since cleared.
The warehouse contained plastic, the fire service said, which caused huge clouds of acrid smoke to spread.
Earlier this month, crews fought a major blaze at a plastic factory in Jebel Ali. The blaze gutted the building and burned into the night.