"It is not painful but it is politically destructive," Peskov said.
Commenting on calls for freezing Putin's assets, the official said that the Russian president keeps money in the Rossiya Bank, which is already under sanctions, Sputnik reported.
Earlier this month, US President Joe Biden did not rule out imposing sanctions targeting Putin personally. This question was also discussed in the US Senate.
Biden was echoed by other Western leaders, who also have pledged "grave consequences" for Russia should it attack Ukraine.
Moscow has repeatedly slammed what it described as "anti-Russian hysteria" in the West, saying that it has no plans to invade any country and stressing the fact that NATO's military build-up close to Russian borders was posing a threat to the country's national security.
Russia has also explained numerous times that it has the right to move its own army wherever it wants within its own borders and this should not be a matter of concern to anybody.
Earlier, Biden said that Putin would face "sanctions he has never seen" in the event that he decides to "invade" Ukraine.