A Bola reported that the 57-year-old Portuguese coach has held a meeting with the Iranian football club.
He had been previously shortlisted to coach Iran’s Esteghlal.
Jose Morais has most recently worked as head coach of Saudi Arabian giant Al-Hilal.
Morais has also worked in Inter Milan, Chelsea and Real Madrid as assistant coach.
Sepahan is without a coach since parting ways with Moharram Navidkia in early June.