Team Melli is drawn into Group B of the 2022 FIFA World Cup, alongside England, the US and Wales, while Senegal will face Ecuador, the Netherlands and host nation Qatar in Group A.
Carlos Queiroz's side picked up its first victory since the end of the FIFA World Cup qualifiers as it edged Uruguay 1-0 at the NV Arena in Vienna, Austria, last Friday.
Senegal also cruised to a 2-0 victory over Bolivia when the sides squared off at the Stade de la Source last Saturday.
Iran will head into Tuesday on a run of just two defeats across all competitions since the start of 2020, claiming an impressive 16 wins and one draw in that time.
Iran will be making its seventh World Cup appearance in Qatar,
Aliou Cisse's side, who secured its first Africa Cup of Nations title in February when it beat Egypt in the final, is now unbeaten in 15 of 19 games across all competitions in 2022, claiming 13 wins and two draws since the turn of the year.