In the match, held at the Estadio do Dragao, Otavio opened the scoring just a minute into the match.
Taremi was on target in the 18th, 34th and 50th minutes.
Jerome Opoku scored an own goal in the 70th minute to make the scoreboard 5-0.
Bruno Marques scored a consolation goal in the 75th minute.
Porto is second with 32 points.
Benfica leads the table with 37 points with one game in hand.