New Technique to Help Brain Cancer Patients

New Technique to Help Brain Cancer Patients

TEHRAN (Tasnim) - A new scanning technique reveals how susceptible patients with aggressive brain cancer are to the drugs they receive.

The new scanning technique developed by Danish and US researchers and the research behind the ground-breaking technique has just been published in Nature Medicine.

Each year sees 260 new cases of the most aggressive type of brain cancer in Denmark. Some patients survive only a few months, while others survive for 18 months. Only very few, 3.5%, are alive five years after their diagnosis.

A new scanning technique can now reveal how the brain tumour responds to the drug administered.

"We have developed an MRI technique which reveals how a patient will respond to the treatment that inhibits the growth of new blood vessels to the tumor. The technique allows us to only select the patients who will actually benefit from the treatment and to quickly initiate or intensify other treatments for non-responding patients," said Kim Mouridsen, Associate Professor at Aarhus University and head of the research group Neuroimaging Methods at MINDLab, Aarhus University.

Aggressive brain cancer is usually treated with drugs that inhibit the growth of new blood vessels, as the most aggressive brain tumors are constantly trying to produce new blood vessels to get oxygen. The treatment alleviates the symptoms, but it also increases the efficacy of radiation therapy because it improves oxygenation.

According to Kim Mouridsen, the new technique -- Vessel Architectural Imaging -- is an important step towards better treatment.

"Getting more knowledge about what the blood vessels in the tumour look like will also give us a better understanding of the mechanisms which are decisive for the efficacy of the treatment. And understanding these mechanisms is precisely what we need to be able to develop and improve the treatment of brain tumors in general."



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